DM Testresults

[mijke]

Thanks again Satu for sharing open ALL your test results!

[Vaiva]

Originally Posted by mijke

Thanks again Satu for sharing open ALL your test results!

Really - this is great when people do not hide the results that may seem "not so nice". It is a pitty many still think it is some kind of shame or what We should maybe talk more about it - that DM/DM does not mean any tragedy

[doublewolf]

From Italy:
BEY' CHEE DOZZ DE LA MOLLYNIERE DE LO SCALE
DM TEST GENOTYPE N/N

[Lorry - MLS]

Dheer'Syb Ooh de la Mollynière de Lo'Scale : N/DM

Thalia Crying Wolf : DM/DM

[*Satu]

Originally Posted by Vaiva

that DM/DM does not mean any tragedy

Yes. This is not a big tragedy. In this moment puppies whit Baron all is only Carrier.
And Baron/ Elys all tested dogs are carrier.

I´m waiting for a more older dogs have DM results and breeders who have many litters in year make tests very soon.

[Hanka]

Hi Lorry, I wish to Thalia maximally health life. I hope DM will not be visible on her too.

[Lorry - MLS]

Originally Posted by Hanka

Hi Lorry, I wish to Thalia maximally health life. I hope DM will not be visible on her too.

Merci de ces quelques mots de soutien Hanka ....ça me touche ...

Thalia, vient d'avoir 5 ans en Février dernier, elle est en pleine forme et j'espère qu'elle le restera encore longtemps ....

[Lorry - MLS]

Thalianounette ....

[Backman]

DM results from kennel Forever Wolf !


Blazy de la Louve Blanche
Degenerative Myelopathy - PCR
Result Myelopathy
Result: Genotype: N/DM

Dream Wolf de la Louve Blanche
Degenerative Myelopathy - PCR
Result Myelopathy
Result: Genotype: N/DM

Forever Wolf Arctic Hero
Degenerative Myelopathy - PCR
Result Myelopathy
Result: Genotype: N/N

Forever Wolf Arctic Angel
Degenerative Myelopathy - PCR
Result Myelopathy
Result: Genotype: N/N

Crying Wolf Luka
Degenerative Myelopathy - PCR
Result Myelopathy
Result: Genotype: N/DM

[z Peronówki]

Originally Posted by Hanka

Hi Lorry, I wish to Thalia maximally health life. I hope DM will not be visible on her too.

Hanka, now a serious question - do you know PERSONALLY at least ONE Wolfdog who has any VISIBLE problems with DM?

I know some Wolfdogs which are moving really horrible but they are N/N....

[Hanka]

I never had seen (on my own eyes) wolfdog with visible problems because DM.
Why you ask ?

[CDaniela]

CSV are testing a single mutation in the SOD1 gene (considered a major risk factor at the moment). I think that in the future, discovering another SOD1 gene mutations that will affect the expression of the disease.

[z Peronówki]

Originally Posted by Hanka

I never had seen (on my own eyes) wolfdog with visible problems because DM.
Why you ask ?

Honestly - because I think we should not wish "long life without any symptoms" to any DM/DM dogs... In the most cases I would rather wish other (sometimes N/N) dogs to move in the old age as good as some of these DM/DM dogs...

Best example - Baron....
His father Gaius was living 14 years and till the end he was pretty good moving dog ("extremly good moving" when we take into consideration his age). When he was over 10 years old he was still moving much better than many YOUNGER (5-6 years old) dogs which we can see running in the show rings...
Dia Kollárov dvor at the age of 10 years is moving like young female and she is still alive (trying to beat Gaius? ).

For sure you know how many dogs are not so lucky - they are much younger but show already symptoms of degenerations.

The problem are really not the dogs with DM/DM which move simply great (and where selection will be done) but the dogs which are N/N and are used as pupular stud dogs even if they move like cripples...

[Gypsy Wolf]

In GSD, the current "theory" is that up to 25% of the population is DM/DM. Not all of those GSD develop DM symptoms, though other things may kill them before the disease manifests itself - things like bloat/gastric torsion, for instance, may kill a GSD before it ever shows symptoms.
I also would like to know (if possible) how many DM/DM CsVs end up getting symptoms. The information on diet and lifestyle may affect whether or not the disease manifests.
CsVs live longer than the typical GSD and perhaps the "wolf" genetics protect them from symptom development to some degree. We will only know if we collect information. Knowing these factors could very well positively impact not only CsVs with DM, but GSDs also (who seem to have a higher rate and more severe cases of DM symptom development).
If we surmise that CsVs (due to their genetic heritage) have a similar percentage of DM/DM animals (25%) but far fewer actual cases of disease symptoms, we need to look at outside factors that may influence disease development.
As it is now, the GSD community as a whole, seems to be ignoring the genetic test, citing that not all DM/DM dogs get DM symptoms. Obviously there are other factors at play that trigger disease development. By collecting as much information as we can (even though at this point it is "anecdotal" and not truly "scientific") we may be able to see some correlations or trends that can be studied more in depth - without open discussion, though, we simply bury our heads in the sand...
We are all stewards of our breed(s) and need to look at the big picture rather than any "embarrassment" over whether or not our dogs have DM (as if it is our fault!). I would encourage those who have dogs with DM/DM results to carefully note diet, health and environment and perhaps even donate tissue samples for further study so that we can all learn and perhaps remove this debilitating disease from our breed.