DM Testresults

[elf]

D'autant que tous les chiens porteurs ( qui vivent chez moi) sont ou seront systématiquement stérilisés, les uns derrière les autres....

Which would be not the right breeding policy. Too many dogs in the breed are carriers. Also I would like to inlight that, as the DM test is good to have, it's currently an incomplet test, other genes/factors are involved to develop the disease (+ highly presumption that N/DM can also devlop the disease). So sterilize all N/DM is not the right solution.

[Lorry - MLS]

Originally Posted by elf

So sterilize all N/DM is not the right solution.

D'après vous, vouloir stériliser tous les chiens porteurs (N/DM), n'est pas une bonne solution ?.

Vous avez peut être raison .... mais à mes yeux, quand je vois le % des chiens qui s'avèrent finalement porteurs, issus par exemple d'un seul de mes reproducteurs mâles, porteur lui aussi, je l'estime trop important, pour jouer à chaque fois à la roulette russe....


Pourquoi, refaire des portées avec un mâle porteur (avec une femelle saine) et prendre d'avance le risque de générer de nouveaux porteurs. ???
De même, comment réusiir à assainir son cheptel, si à chaque fois, on réitère les mêmes erreurs (des mariages à risque )...?

Sincèrement, je n'en vois pas l'utilité .....En tout cas à mon niveau personnel et avec mes propres chiens ....

Pour le reste, je laisse à chacun, le soin de décider en son âme et conscience de ce qu'il convient de faire (ou pas) pour le futur de la race ....

[elf]

IMHO it's important that breeders realize that they can keep N/DM dogs in breeding program as such dogs may have others very positive part therefor are important for the breed (in addition at the end 50% of CSV may be carrier).
I really understand breeders want to "clean" their own kennel but if you look at how distributed control work (e.g. emergent behaviour) you will see that each one action is important. This has already been done in the past (sorry I forgot the breed name) this breed was affected by an eye disease, the breeding club + breeders follow a restrictive breeding program, at the end the disease almost disappear so this has been 'working', but what this gene narrowing bring to the breed is another new eye disease more serious than the other one. The DM test result is just another part of the breeding value of a dog, but not an absolute 'not for breeding' mark.

[draggar]

I agree, elf. There are (IMO) more improtant factors that need to be looked at like hips and elbows. Relatively speaking, DM is rather eacy to breed it out, any breeder can eliminate the disease on one generation (breed an a/a to a N/N - all puppies will be carriers) and eliminate the genes themselves (affected and carriers) in two generations.

Plus, it doesn't look like as high as a percentage of affected vlcaks contract the symptoms as in other breeds like Germans shepherds and they've noticed dogs who were on a diet where "fats" were listed early in the ingredients list had a much higher chance of developing symptoms.

The gene pool is too small, especially here in the USA, to eliminte any dog solely on their DM test results (but it is still extremely important to keep track of it!).

[Lorry - MLS]

Il va de soi que votre façon de voir les choses (et d'en tourner l'explication) va au final faire plaisir à plus d'un éleveur !

Chouette continuons de reproduire !

[wera]

exactly that was and is an apprehension of many breeders.
the only one mated N / N and by that, then the problem of inbreeding with their years and gets in a few episodes.

if the mathematically about 50% are from an N / DM x N / N breeding N / N.
then you have a couple of years away and the opportunity to get to race clean without the gene pool to shrink too much.

and there are many more points which are to be observed in a breeding. This includes HD, ED, standard and character, inbreeding, ect.

I think we are on the right path but it was also only a "small" number of dogs tested in relation to the total population

[Sherdor]

The 2 safe puppies (N/N) i have in my litter tested are very different than the others... they look like weaker than the carrier (N/DM) or the affected male (DM/DM) ...

That also means that a lot of gene are linked to the mutated SOD1...

... and if in one hand you think you could be safe according to DM disease, maybe in other hand, you can select also weak point of the breed !

(maybe it could also be coincidence... but who knows ?)

[elf]

Originally Posted by Lorry - MLS

Il va de soi que votre façon de voir les choses (et d'en tourner l'explication) va au final faire plaisir à plus d'un éleveur !

Chouette continuons de reproduire !

Here is what Joan R. Coates said:

"The 'DM' allele is very common in some breeds. In these breeds, an overly aggressive breeding program to eliminate the dogs testing DM/DM or N/DM might be destructive to the breed as a whole because it would eliminate a large fraction of the high quality dogs that would otherwise contribute desirable qualities to the breed.
...
Summary: We recommend that dog breeders take into consideration the DM test results as they plan their breeding programs; however, they should not over-emphasize this test result. Instead, the test result is one factor among many in a balanced breeding program."