Health results (also DM!!) in the Wolfdog.org database

yukidomari · 13-01-2011, 01:58

Quote:

Originally Posted by saschia

Well, I can imagine multi-drug resistance in cancer cells and in bacteria, but in dogs???

Unfortunately Australian Shepherds are in my experience the breed with the highest incidence of MDR1 mutation. Chemicals commonly found in heartworm preventatives can be dangerous when applied on dogs with MDR1 mutations (along with other chemicals). Lots of Aussie owners we know purposely stay away from medications with Ivermectin in it, even if they have not tested the specific dogs for MDR1 mutation.

saschia · 13-01-2011, 08:53

Thanks for clearing up. So it is not resistance, but sensitivity, actually... Very interesting...

michaelundinaeichhorn · 13-01-2011, 09:03

Is there any known wolfdog that has shown MH or MDR1 mutation? I know that this can occure in GSH but never heard of a wolfdog.

13-01-2011, 08:53	#2
saschia Member Join Date: Sep 2003 Location: Bratislava Posts: 936	Thanks for clearing up. So it is not resistance, but sensitivity, actually... Very interesting... __________________ Saschia (Sasa Zahradnikova) http://www.chiens-loup-tchecoslovaqu...ei-et-damon.ws

Thread Tools
Show Printable Version Email this Page
Display Modes
Switch to Linear Mode Hybrid Mode Switch to Threaded Mode

13-01-2011, 09:03	#3
michaelundinaeichhorn Senior Member Join Date: Sep 2003 Location: Bad Dürkheim Posts: 2,249	Is there any known wolfdog that has shown MH or MDR1 mutation? I know that this can occure in GSH but never heard of a wolfdog.