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Originalmente publicado por mijke
MDR1= Multi Drug Resistance
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Well, I can imagine multi-drug resistance in cancer cells and in bacteria, but in dogs???
Malignant hypertermia - is there a valid test? As far as I know, malignant hyperthermia is caused by mutations on RyR1 gene... If it behaves similarly to RyR2 gene, than any testing is quite a lot of work, as there are more than 50 different RyR2 mutations (causing CPVT) in people identified so far, in 3 different regions of the gene, and RyR1 as well as RyR2 are huge genes. Or is it identified by encountering the problem and subsequent muscle biopsy?