DM Testresults

[massimo]

One last comment, then I will return to my long and healthy absence from this site.
I believe that a breeder that "produced" DM/DM dogs has nothing to be ashamed about, he simply wasn't lucky. On the other hand, a breeder who has only N/N dogs was just luck, not a cool breeder.

As already mentioned by Daniela, there is surely another factor than merely the SOD1 gene, and this factor has not been found yet. Let's call it factor F.
Only when Factor F is combined to SOD1 gene, the illness will occur.
It is therefore important, TODAY, from a medical point of view both the SICK dogs (DM/DM and Factor F) and the healthy but positive dogs (DM/DM but no factor F). So testing our dogs is important to help the research MORE than just avoiding to have sick dogs.

As for Breeding and Breeders, DM/N dogs should be used freely in breeding but with a careful attention, and I believe also DM/DM dogs should be used as long as we avoid to produce DM/DM dogs.
Don't forget that from DM/DM dogs also non positive dogs can be born, and with a correct breeding the DM gene can be even eliminated after the second generation.
My Jasna is PROUD niece of Baron Spod Dumbera and is N/N. I am glad he was used in breeding and that he wasnt STUPIDLY cut off.

I believe it is DUTY of a breeder, today, to do the maximum he can to avoid producing DM/DM dogs, but I also believe that it would be a CRIME and DESTRUCTION of our race if breeder used ONLY N/N dogs in his breeding plans or if owners bought ONLY N/N dogs and avoided the DM/N ones.

Goodnight!

[Enid Black]

Massimo, I hope Lunatica will be healthy for all her life!

As for you reflections, for example Spettro is grand grand son of Baron, Spettro's mother is his grand daughter and she's N/N too, so I am happy too the he's been used and I think that the right thing is to test as many dogs as possible without making a witch hunt. Testing is fundamental I still think. Research is too.

I still wish a healthy life without the F factor to every DM/DM dog.

[Hanka]

Hi Massimo, I cross fingers for Lunatica for maximally health life.

[Shadowlands]

Well said, Massimo. We narrow the gene pool far too much if we avoid using dogs because of a 'bad' result. People have been saying that an N/DM + N/DM breeding will produce 50% affected dogs. Surely, statistically, it would be 25% affected, 50% carrier and 25% free? So by avoiding these breedings, we deny the existance of healthy pups who can carry on the diversity of the gene pool.

PS Everyone. I have never studied genetics so please excuse me if I am wrong and let me know where I have gone wrong.

Love to Lunatica x

[Rona]

Originally Posted by massimo

.
Only when Factor F is combined to SOD1 gene, the illness will occur.
It is therefore important, TODAY, from a medical point of view both the SICK dogs (DM/DM and Factor F) and the healthy but positive dogs (DM/DM but no factor F). So testing our dogs is important to help the research MORE than just avoiding to have sick dogs.

This was exactly the point Margo was trying to make. We don't know what the role of factor(s) "F" is in DM activation!
Until it's discovered (in the medical sense), all information can only be obtained from the owners and vets of DM symptoms affected dogs and it's a pity so few of them have the nerve to share it.

All the best to Lunatica. I'm sure she'll be fine!

[Lorry - MLS]

Forest de la Mollynière de Lo'Scale : N/DM