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Any puppies sold during the "transition" period (while the new breed is being engineered (for the lack of a better term) should all be spayed / neutered when they reach the correct age.
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Well not any but yes most. Only not the ones you want to use for using your word the engineering for the breed.
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Every breed has it's reason and purpose and IMO the only acceptable reason to cross breed (any breed) is to create a new breed that fills a gap in the dog world. Breeding cross-breeds for money or just ease IMO is unethical to begin with. "They make good pets" is not a good reason.
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Besides good pets the breed was original started for a better sled-dog.
I find a pup going to his new home with 5 weeks way to early(at the earliest point I would say 8 weeks and no sooner). And if only used for house-dog I agree with you that it is better that they all be spayed / neutered.