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Old 09-01-2010, 10:22   #35
michaelundinaeichhorn
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Join Date: Sep 2003
Location: Bad Dürkheim
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To do a test you have to know exactly what gene causes the disease, so first you start with finding out if a disease is inherited and which way is likely (recessiv, dominant, autosomal, etc) than you need to find out which mutation of a gene ore genes (more often and much more complicated) causes it. For that you need a group of dogs with this disease. Then you build up a test for marking this mutation, then you verify the test for the breed you worked with (look if it really shows all carriers and ill dogs), the you make the next step to find out of the same disease is caused by the same mutation in different breeds (what is very often not the case!) and verify it for different breeds. This takes very often years.

You are carfull in publishing during this period because very often there are different groups working on one problem and who is succesfull first earns the money and the fame.
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